|
KMID : 0364519940050020021
|
|
Dong-A Journal Medicine
1994 Volume.5 No. 2 p.21 ~ p.26
|
|
|
In Vivo Lethal Effect of Hemolysin Produced by Vibrio vulnificus
|
|
|
|
|
Abstract
|
|
|
This study was done for the identification of the main pathogenic factor of Vibrio vulnificus contributed for the lesion and lethal effect of mouse, The injection of 45% ammonium sulfate(AS) fractions of Vibrio vulnificus culture supernatants
into
mice
showed that the lethal factor against mouse was in culture supernatant,
By using the activity differences of hemolysin according to the culture period, and the specific blocking actions by its specific characteristics, it was found that the major lethal factor against mouse was the hemolysin in the culture
supernatant,
It
was confirmed by in vivo blocking assay by injecting hybridoma cells which are producing monoclonal antibodies against Vibrio vulnificus hemolysin,
|
|
|
KEYWORD
|
|
|
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|